| Brand name | ActiTide-3000 |
| CAS No. | 7732-18-5;56-81-5;107-88-0;9003-01-4;9005-64-5 |
| INCI Name | Water, GlycerinButylene glycolCarbomerPolysorbate 20.Palmitoyl Tripeptide, Palmitoyl Tetrapeptide |
| Application | An anti-aging product for face,eye,neck,hand and body care. |
| Package | 1kg net per bottle or 20kgs net per drum |
| Appearance | Semitransparent viscous liquid |
| Palmitoyl Tripeptide-1 | 90-110ppm |
| Palmitoyl Tetrapeptide-7 | 45-55ppm |
| Solubility | Water soluble |
| Function | Peptide series |
| Shelf life | 2 years |
| Storage | Store in cool and dry place, away from light. 2~8℃ for storage. |
| Dosage | 3-8% |
Application
Actitide-3000 is mainly composed of two palmitoyl oligopeptides, palmitoyl Tripeptide-1 and palmitoyl tetrapeptide-7. Actitide-3000 shows a perfect effect from gene activation to protein remodeling. In vitro, the two oligopeptides showed a good synergistic effect in promoting the synthesis of type I collagen, fibronectin and hyaluronic acid. Actitide-3000 is a segment of less than or equal to 20 amino acid sequence, which is the hydrolysate of skin matrix before wound healing.
Collagen, elastin, fibronectin and fibrin hydrolyze to produce soluble peptides, which are autocrine and paracrine regulatory messengers and can regulate the expression of wound healing proteins. As the hydrolysate of extracellular matrix, active peptides are concentrated in the wound immediately after matrix hydrolysis, causing a series of reactions, so that the living tissue consumes the least energy to heal the wound quickly. Actitide-3000 can feedback regulate the process of connective tissue reconstruction and cell proliferation, and produce a large number of skin repair proteins in the process of skin repair, which are more than those in the normal physiological cycle. However, with the increase of age and the decline of many cell functions, the function of skin system decreases. For example, glycosylation disrupts the recognition site of the appropriate scavenging enzyme, prevents the enzyme from modifying the wrong protein, and slows down the skin repair function.
Wrinkles are the result of poor repair of skin lesions. Therefore, actitide-3000 can be used locally to restore cell vitality and achieve the effect of removing wrinkles. Actitide-3000 can be added in appropriate proportion to get good cosmetic effect, which shows that actitide-3000 is not only stable and fat soluble, but also has good skin permeability. Actitide-3000 has the characteristics of biological imitation, which ensures its good safety compared with AHA and retinoic acid.
